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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '066e608baaf6a452d633797099d522720a77bf9b70376574f405a12984c09e6b' 
  AND token = '3wQDbNH6lUPVY0wg7iywe09iw/hPBMJfHHU0Ex13fvs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}