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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6863d96465a9caeb2cdaf791c4fc158337e766a742aa2f7a715b4f4105aea1c1' 
  AND token = '1MJPScX0BBEqV6eIJQph7qC07EGw9momyEuckGmnGmU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}