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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f224a2dec9203d44dfdf70e233629ae18903d50ad6c06cac6c9a7f059a08d520' 
  AND token = '/tVkao+PHPFF6ufkl6n4lvtTpCpR4jJ79ORvbp8IXtc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}