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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '827db1d9cc668ab16166121abc508dd67ec1c7abc988fef3dff3da5cb928d656' 
  AND token = 'XdyfE94s0ZB7T0qa1D/XWa5PXMKScwVlsVGVrPy4G+Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}