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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f9185e6e1815b1d36ea577e5abb75b913e1aa4051103b292c4a979084e1fd2b' 
  AND token = 'ZJz7QZswJzSgZK3L5aGen726qhVQ1Dr61R2oqhEBPwg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}