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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c9389b2288f8290609ed3b8656237cdf7cf4d922ed98d96cadd2a81dfbc83169' 
  AND token = 'pLjB8Xpt/sAsEwE/sbqzOLrH5k1SpRXybbUuBFqgp/Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}