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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fd6ad1c0d5fce9f1a140069ddf794e6144fceb1224f96f607a43c8fb7fd3a676' 
  AND token = 'lo1bnaAcVZ03aphSlVyay71zd1/KsKx4gtLHu1kPTTw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}