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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45a9c0c0a67aadb8950673c51483d7188b6579750fd0b84c07b3be2e924b1f0d' 
  AND token = 'LHL83/QdMQ6qKAt/koX+0KvW2Y2S6VXxys8tynCe7bE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}