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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd0f6cc528ee903982584fcb5e2e953f2cfd9703f02fecb075caa122152dd7d63' 
  AND token = 'ST/M+28jx1Mlbla5ObrTd1jE9RIfhtxWCOd9wwdbCVc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}