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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59cb42058e0f4800066d3a5d2abe931a4062c26b5ee2f1f8b5191f9c506edfc1' 
  AND token = 'gCBbZPiByKoR0X6WbeUrZN1xb5VWsGoKLSuCj+6w+xU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}