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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a69fb5b743c784a1d1cfabb41c521e3e079d6b0f76b66e867aab3dfc287708f' 
  AND token = 'n1mvsIoB388lHbwpQQ6nvH3iEVkAOvc+vgC8m7/9ogo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}