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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a903e2441e75ce5a21cacf09c1ac4cae11e2dae6a648f3f71ed8cd12553af48' 
  AND token = '666vJIJKx95qgFpNr8yQqUuHoERE0oHh69WCTxus/+8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}