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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed32e990859373258080fc103f2d2c1a8363deaa2b5fcea87fb3d704b28335cb' 
  AND token = 'B1HlS0tyk2TP+p+Ksbi+wXWpRsJQW4DtsUut5lMIE94=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}