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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6d22e2c1c6be043b7021436909410df32b90fb26db881db320d9293e6990143' 
  AND token = 'wz5ogZ5mllQxblyzRiYk1wZLnLy6U/xol6I+X1zYoB8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}