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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '401d4f56c57d4a2e5ab38b0cc63cccdf98fbb5bb25fe04ed7292e9a921066c07' 
  AND token = '+0PuujmztS2srAx1rWtd94bPB9CGcvGkptVA6CcRN9E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}