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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80c795d3c4db2ad989f7f7e8e00f466af2cf4544b34942c6cf901461b67f5c08' 
  AND token = '+O0uVE2MrRxUIQNnS4Wg67hGOETOk2jDL0xYkEP2oek=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}