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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b111e7f7a5cdc697a389479200f7976820b55bf2650b42e81269e6011bd8b2de' 
  AND token = 'oH7unSwjIxcAY4YuPOim7E3TiFduxmVAlaHfMOG7bvc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}