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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8465c9085b01b7fde865c643ce0c27380e68dc1fbdf7fcb5c555551c99418e4' 
  AND token = 's20ABMpvpiN3BESE8079WFsxQFqsXWk3edH5OK5+g14=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}