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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8356bc08a876416ef8b79a01a4503a948d0ace0cc49df545c86125589aae5bae' 
  AND token = 'FkFtttFNjuLKwZG2LJ4e8YbwFhvg3uFq5AMl+uMTmo0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}