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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a242447dec0967331fb10d72363e1e0ec1b191cc53c17e3e65f258fd41630901' 
  AND token = 'mZdS+8MQe8OHd5YcBe9F7XFCdDU9+MjqVkc/Z4l6yhM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}