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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '551ef65bf014a62e281dad3f75c72bf8a86f2074cd568dd8316176d7f01351bb' 
  AND token = '+6elXlD82v9coqnwRSQjVbnH+CpqleFAnz/3i7ouDpA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}