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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e69657954c5ed5e2523fa412f4e0e1e412591f47f659dbe9b625bc3989f7aaa' 
  AND token = 'HBE7g9K1Q2x1+qVMGpBEMPNGeznNb4Qm7/Gz778Tu6U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}