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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '149db01b302b5e191d3ad23517f90bb211b85e24500a6b85a2f17a3ed257a1c7' 
  AND token = 'rdB2xUS6TX6h3+ECzTBVoLHRCiuHm9PQuRjw142e4Ak=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}