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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f700ae40d0998e2c551eefd3e0e1408368837f7ec959a550a262a3daa9f36bca' 
  AND token = 'kelUIMmt10l7fj1vHhs/DqlpAYZ+M2iFFDB+xyFMDkw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}