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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37e8b417db216bff3d2686fd86eaa1a10e02ca35c4849a9adcaf8645e5e2ca49' 
  AND token = 'yJatya4NvJKQzpFTv9VHLFTJ7FkiAw5+vSLF1dK5jYg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}