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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b228bfbd487b8144f7e4fdfa048a625f0b4d5c7036cd9a4566658036cfcea7b' 
  AND token = 'aMGlKuZVQyCsvvj+xGtaAWIhS8R50EOXz3mHtZ5y80s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}