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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51d9d2c2b67c070973c8fac3a8732e70f4a1e74a3034a074aa9a295fbea67364' 
  AND token = 'efj7R+KY/QS2DQV1Fl7A22R6uhmyjnZXZbroLTeaIlM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}