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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f1007b1d070edb3beeca818191e46d8ff5ce40eede8a12f6f51cc987eed6840a' 
  AND token = 'qMNvQvhF2xZVObiIiCKXjzH3bOoSUgmg8lKSo1eHRaA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}