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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e7139a7cbd231d9fdce13c5d789e6420127c023548af5299edde29b3f0a46bfa' 
  AND token = '4lBPEPQiBoBoC95I9mXuNdsZqTPNUminq2mE/7WZ8go=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}