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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6662099621d313888d62263c5912918aad268f16a6248f7960f82684197c6880' 
  AND token = 'y4KWTYPGSS6VRRjl4fkTHaXd8lFxSl+VxhXoYh3jaY0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}