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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bc1a19072dae858aef21b7eab26de17b80b43ae79cf23965f4739294c74a19b8' 
  AND token = 'U1MHmiWunT3OoL2mmuPO4flb3zMq2lrV3cXiv13HOb4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}