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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f5ceea51743c96e57fe1211b7f73effdd6d8bc051e23185d22e6d1968fa71a86' 
  AND token = 'NtpUE4a0x+o6TU8RkzEIXNXE+qZiqfh0rbrgMBx1k1U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}