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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5655653ee46c904fdb89d9035c1d716d2d1a3dbf05c1025e866e4829df85d0bf' 
  AND token = 'UT+j1W81XQZ2AdqVq4Dc5HB8yQFHfxmQqcZw5KgDlP4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}