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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '69b72b6a08c666e43ece48f1325e4d68d3c73bf25167ebba05247eef6532a603' 
  AND token = 'jJH30dAEt8lkBNXKPF3HSd9fxF/DXEhQb8xuFiSEl5Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}