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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a5699c5025b4ca5e1e3d1249a2c92e6182b46f132e9e2d6d916c21f9998e1d0' 
  AND token = 'E65wWM1Q+RyTyI1BXpAEWMqVdlD2AVqrzHZ8dznWBmo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}