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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '257526cedf9b1f87b5dc6b7aa6ec44e8e53bfc1793583d0c06cf7916bd2f4419' 
  AND token = 'xi+tcAslUXM0aCmeB5jAQrBPXjD3Rg2dU/gsOGDvBcM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}