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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '76e82a45a4cb06a222adeecc6ccdf1866db0e5961cc05ec1219eb12586d6b590' 
  AND token = 'VJ7QRLxnTgh3Gc/D+XQXFR6rZDnsLxptBUgFOHW3rac=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}