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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'afdf6f63469bb264778d909c23db9e1c7b8717f81a322635750911027bd41814' 
  AND token = '0jer7Cy0bPV41ReV+4bm/YikxlSs0fXAqHYhEjwDTbE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}