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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b52100bd2259c0fc3e5c2184ff7f6b5e504b5e32c4dafb7ec04923614223458' 
  AND token = 'kkLfNGOJW3dkhNLyMhV3ZzfMB6mqvXM3pzVKNDev0B8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}