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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7cfefd274e71b51d4aca2fd6ab6127523fb1df8bb94e3fca1b5ecc1244786d4b' 
  AND token = 'sPOvBxslRqkzxKOfJ+oNp9H1XmXis3kASUM14SbO6PM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}