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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '492a84f4b52808540042a4c75160216c9c60c05ff9dd83919d545d782c8ace99' 
  AND token = '5p9QEWpOIoOY9PQP+up4iOeFm0FrleHxBx2k9cpKMms=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}