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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '549fd38e3729cb0bafdc7895a3124234fc69447a5c443f55c9a536af1a63f800' 
  AND token = 'Efr2fV/tDKIiEfCrfmNzRweZpOdOY14sSTXP2wkk1qA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}