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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b516e1ab258ce59768e2c088b998b80720d97de38b75e24d722863e56ed2397' 
  AND token = 'iIECV6MTrkumXPn0l2htIgdHdlg5+F1slqB6tmq1NVI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}