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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e085fb5750d0a051ad5c25206f1dcf92c6d77fadbc15c2fcd38778933bc91e4' 
  AND token = 'b/JVGZSFHg9xyqStHnwr+CFlNdMDBAC5uNF5jH5bPFw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}