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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd8e42e83d2f41b898e67c0c4c0faf7520397fe5288531df717a256ca737cfeaf' 
  AND token = 'cw9mEFZZuiYpoxoIl+7g+ZdpfsilG5qXTnOaCg34pLI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}