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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a366eda2072b2a370b93ab7c9cb1d1af0fbc5694fdcb2cd14ce70148bc618b32' 
  AND token = 'cDGhXx1+kh1hv7a0y1nTJ9PEBNEAqZw6nA/xqQyMFLc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}