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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d2e7355d475f1a96ddb46506f45a5ea181ccc302c7aacb0012247938648002e' 
  AND token = 'dDyDo8AyPOJSH2fGxjvQMpE3S7ek+65pSH07UOkVXYs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}