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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'acca16ff285e950a13cbca9beec807e0ae3a7c2069f078ca6153561d87fd4ffc' 
  AND token = 'joZuGSGyUKmRCp+nfY5Vv1QZHHKlByeZFkbi7djI7+Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}