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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f56a29220f8a3641d0831f619c22d47f26688b04aded1e1fb33fe2d19842c66' 
  AND token = '0o/BA6MI6DLIpJWUZePgxjbQVCsnJJGVdtZnhIJHWN8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}