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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f3e47854cab1ca1aff760746faa2875b0e93b23e62da0ac068ea209871238a8' 
  AND token = 'b/mGxk2eg7iGgh69R3/+PPNSQQv9gBJB3PkYtK+ET8E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}